MovDisordV3, Main, Exploration, bibRecord, 002D53

Management of status dystonicus: Our experience and review of the literature

Identifieur interne : 002D53 ( Main/Exploration ); précédent : 002D52; suivant : 002D54

Management of status dystonicus: Our experience and review of the literature

Auteurs : Paolo Mariotti [Italie] ; Alfonso Fasano [Italie] ; M. Fiorella Contarino [Pays-Bas] ; Giacomo Della Marca [Italie] ; Marco Piastra [Italie] ; Orazio Genovese [Italie] ; Silvia Pulitan [Italie] ; Antonio Chiaretti [Italie] ; Anna Rita Bentivoglio [Italie]

Source :

Movement Disorders [ 0885-3185 ] ; 2007-05-15.

RBID : ISTEX:FD75363227488BFAD946540B6315A4106C69831B

Descripteurs français

Pascal (Inist)
- Conduite à tenir, Dystonie, Expérience, Midazolam, Pantothenate kinase, Système nerveux pathologie.

English descriptors

KwdEn :
- Adolescent, Clinical management, Dystonia, Experience, Humans, Male, Midazolam, Nervous system diseases, Pantothenate kinase, Spinal Dysraphism (therapy), dystonia, dystonic storm, midazolam, pantothenate kinase associated neurodegeneration, status dystonicus.
MESH :
- therapy : Spinal Dysraphism.
- Adolescent, Humans, Male.

Abstract

Status dystonicus (SD) is a life threatening disorder that develops in patients with both primary and secondary dystonia, characterized by acute worsening of symptoms with generalized and severe muscle contractions. To date, no information is available on the best way to treat this disorder. We review the previously described cases of SD and two new cases are reported, one of which occurring in a child with static encephalopathy, and the other one in a patient with pantothenate kinase‐associated neurodegeneration. Both patients were admitted to an intensive care unit and treated with midazolam and propofol. This approach proved to be useful in the former while the progressive nature of the dystonia of the second patient required the combination of intrathecal baclofen infusion and bilateral pallidal deep brain stimulation. We believe that a rapid and aggressive approach is justified to avoid the great morbidity and mortality which characterize SD. Our experience, combined with the data available in the literature, might permit to establish the best strategies in managing this rare and severe condition. © 2007 Movement Disorder Society

Url:

https://api.istex.fr/document/FD75363227488BFAD946540B6315A4106C69831B/fulltext/pdf

DOI: 10.1002/mds.21471

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en">Status dystonicus (SD) is a life threatening disorder that develops in patients with both primary and secondary dystonia, characterized by acute worsening of symptoms with generalized and severe muscle contractions. To date, no information is available on the best way to treat this disorder. We review the previously described cases of SD and two new cases are reported, one of which occurring in a child with static encephalopathy, and the other one in a patient with pantothenate kinase‐associated neurodegeneration. Both patients were admitted to an intensive care unit and treated with midazolam and propofol. This approach proved to be useful in the former while the progressive nature of the dystonia of the second patient required the combination of intrathecal baclofen infusion and bilateral pallidal deep brain stimulation. We believe that a rapid and aggressive approach is justified to avoid the great morbidity and mortality which characterize SD. Our experience, combined with the data available in the literature, might permit to establish the best strategies in managing this rare and severe condition. © 2007 Movement Disorder Society</div>
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Movement Disorders (revue)

Management of status dystonicus: Our experience and review of the literature

Management of status dystonicus: Our experience and review of the literature

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Movement Disorders (revue)
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